Heartgard Makes My Dog Sick. If this happens, you’re advised to redose. But, while that sounds useful on the surface, another take home point is this:

Heartgard demonstrated no signs of toxicity at 10 times the recommended dose (60 mcg/kg) in sensitive collies. Heartgard along with a combination of these two ingredients is able to prevent heartworms and terminate roundworms and hookworms from the body of dogs. Angel was given her monthly heartworm drug, became sick from the drug in a serious way, and she was remedied by a substance known to help with detoxification.