Canine Diabetes Urine Smell. Diabetes can cause excess glucose in the dog’s urine, creating that sweet smell. With advanced diabetes, sugar and ketones, which are normally absent, can accumulate in the urine and create a strong odor.

The science of dogs smelling diabetes the science behind a dog’s ability to detect a drop in blood sugar is absolutely fascinating. Other kidney malfunctions can make your dog’s urine particularly smelly, with higher concentrations of ammonia and other waste than usual. Besides causing repeated utis, diabetes can be deadly if not treated.